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Army Medical Research and Materiel Command (USAMRMC) under contract No. W81XWH-15-C-0046. The CRMRP was established in 2008 to foster research and technology advances for regeneration, restoration, and rehabilitation of traumatic injuries. In accordance with USAMRMC guidelines, in the conduct of clinical research, AcelRx has adhered to the policies regarding the protection of human subjects as prescribed by Code of Federal Regulations (CFR) Title 45, Volume 1, Part 46; Title 32, Chapter 1, Part 219; and Title 21, Chapter 1, Part 50 (Protection of Human Subjects). About ARX-04 ARX-04 is a non-invasive investigational product candidate consisting of 30 mcg sufentanil tablets delivered sublingually by a healthcare professional using a disposable, pre-filled, single-dose applicator (SDA). Sufentanil is a synthetic opioid analgesic with a high therapeutic index and no known active metabolites. AcelRx expects to submit a New Drug Application for ARX-04 with the U.S. Food and Drug Administration in December 2016 using the 505(b)(2) pathway. Under these guidelines, AcelRx expects its application to be subject to a ten-month review period. About AcelRx Pharmaceuticals, Inc.
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Such skills as snow shelter building, snowshoeing, and animal tracking will be taught and practiced at a Guided Family Adventure program titled “Winter in Pinkham Notch” over the Martin Luther King Jr. Weekend, Jan. 14-16. A winter multisport Family Adventure program, in which participants have the opportunity to snowshoe in Pinkham Notch and cross-country ski at the nearby Great Glen Trails Outdoor Center, as well as build snow shelters and play snow games, is set for Joe Dodge Lodge over the Presidents’ Day Weekend, Feb. 19-22. During Presidents Week, family programs are slated at AMC’s Cardigan Lodge in Alexandria. Three-day Winter Family Explorations that feature sledding, snowshoeing, animal tracking, and other winter activities are scheduled for Feb. 20-22 as well as for Feb. 22-24 at Cardigan. Feb.
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